UV radiation in combination with Riboflavin initiates molecular cross-linking of corneal collagen. Thus progressive corneal thinning is slowed down or even stopped. Biomechanical strength of corneal tissue is improved.
A number of clinical studies have demonstrated that progressive keratokonus and iatrogenic ectasia can be stabilized by corneal cross-linking.
72-months follow-up data has not shown any decrease of biomechanical corneal stability. More than 50 % of all patients showed a reduction of maximal keratometry. No adverse effects were observed either.
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UV radiation in combination with Riboflavin initiates molecular cross-linking of corneal collagen. Thus progressive corneal thinning is slowed down or even stopped. Biomechanical strength of corneal tissue is improved.